Mouse C-reactive protein (CRP) is a protein found in the blood, the levels of which rise in response to inflammation (an acute-phase protein). CRP is synthesized by the liver in response to factors released by fat cells (adipocytes). It is a member of the pentraxin family of proteins. The physiological role of CRP is to bind to phosphocholine expressed on the surface of dead or dying cells (and some types of bacteria) in order to activate the complement system via the C1Q complex. CRP is a member of the class of acute-phase reactants, as its levels rise dramatically during inflammatory processes occurring in the body. This increment is due to a rise in the plasma concentration of IL-6, which is produced predominantly by macrophages as well as adipocytes. CRP binds to phosphocholine on microbes. It is thought to assist in complement binding to foreign and damaged cells and enhances phagocytosis by macrophages which express a receptor for CRP.
| Place of origin: | USA |
| Brand: | Creative Biomart |
| Price: | Ask for price |
Category: Medicine, Health & Beauty -> Biotechnology
Creative Biomart |
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| Street: | 45-16 Ramsey Road Shirley | ||||||
| City: | New York | ||||||
| Postal code: | 11967 | ||||||
| Country: | United States | ||||||
| Phone: | +1 631 5599269 | ||||||
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Contact person |
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| Name and Surname: | Candy Ton | ||||||
| Phone: | +1 631 5599269 | ||||||